G6PD deficiency, also called favism, is a hereditary abnormality
-it causes destruction of RBC, leading to hemolytic anemia
Symptoms:
- sudden rise of body temperature
- jaundice in newborn
- dark, yellow-orange urine
- fatigue
- shortness of breath- rapid heart beat
It can be triggered by infections, certain food, medicine (certain antibiotics) and chemicals
Food to Avoid:
1. Broad bean / fava bean / kacang parang 蚕豆
2. Legumes 豆类
eg: beans, peas, lentils 扁豆
3. Soy / soya
4. Peanuts / kacang tanah 花生
5. Menthol, menthol-flavoured candies,food 薄荷味的糖果
- can be found in candies, mouthwash, toothpaste, gums
6. Certain herbs7. Also avoid the use of moth balls 臭丸as repellent in closet
Glucose-6-phosphate dehydrogenase (G6PD or G6PDH) (EC 1.1.1.49) is a cytosolic enzyme that catalyzes the chemical reaction:D-glucose 6-phosphate + NADP+ ↔ 6-phospho-D-glucono-1,5-lactone + NADPH + H+. This enzyme is in the pentose phosphate pathway, glycerol 3 phosphate dehydrogenase
ReplyDeleteGlucose-6-phosphate dehydrogenase (G6PD) deficiency affects the pentose phosphate pathway, an alternative pathway of glucose metabolism. G6PD is crucial in producing NADPH, a molecule that helps protect red blood cells from oxidative damage. When G6PD is deficient, red blood cells lack enough NADPH, making them more susceptible to oxidative stress and leading to hemolysis in response to certain triggers like infections, certain drugs, or foods
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